Matrix metalloproteinase-9 expression in pterygium

Arquivos Brasileiros de Oftalmologia

Silvana Artioli Schellini²  Erika Hoyama²  Deilson Elgui Oliveira¹  Carlos Eduardo Bacchi¹  Carlos Roberto Padovani¹ 

[1] ,Universidade Estadual Paulista Faculdade de Botucatu Department of OphthalmologyBotucatu SP ,Brasil

关键词: Pterygium;    Matrix metalloproteinases;    Immunohistochemical;    Recurrence;    Pterígio;    Metaloproteinases da matriz;    Imuno-histoquímica;    Recidiva;   

DOI  :  10.1590/S0004-27492006000200005

来源: SciELO

【 摘 要 】

PURPOSE: To assess matrix metalloproteinase (MMP)-9 expression in pterygium lesion. METHODS: A prospective randomized clinical trial was done to evaluate the expression of matrix metalloproteinase in normal and in primary or recurrent pterygia in Tenon's capsule by immunohistochemical analysis and a computerized image analysis system. The data were submitted to statistical analysis. RESULTS: Matrix metalloproteinase expression showed no difference in normal Tenon's capsule and in primary or recurrent pterygia. CONCLUSION: The similar expression of the matrix metalloproteinase in normal Tenon's capsule and in primary or recurrent pterygia allowed us to conclude that matrix metalloproteinase is not implicated in the genesis or the recurrence of pterygium lesion.

【 授权许可】

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