Cytogenotoxicity of Cymbopogon citratus (DC) Stapf (lemon grass) aqueous extracts in vegetal test systems

Anais da Academia Brasileira de Ciências

Saulo M. Sousa¹  Pâmela S. Silva¹  Lyderson F. Viccini¹ 

[1] ,Universidade Federal de Juiz de Fora Laboratório de Genética Departamento de BiologiaJuiz de Fora MG ,Brasil

关键词: aqueous extract;    Cybopogon citratus;    cytotoxic effect;    genotoxic effect;    Lactuca sativa;    extrato aquoso;    Cymbopogon citratus;    efeito citotóxico;    efeito genotóxico;    Lactuca sativa;   

DOI  :  10.1590/S0001-37652010000200006

来源: SciELO

【 摘 要 】

The lemon grass, Cymbopogon citratus (DC) Stapf, is an important species of Poaceae family commonly used in the folk medicine in many countries. The aim of this study was to investigate the cytotoxic and genotoxic effects of aqueous extracts from C. citratus leaves on Lactuca sativa (lettuce) root tip meristem cells by cytogenetic studies that have never been done before for lemon grass extracts. For this, lettuce seeds were treated for 72h with different concentrations of lemon grass aqueous extracts (5; 10; 20 and 30 mg/mL). The percentage of germination, root development and cellular behavior were analyzed, and the results showed that the highest concentration of aqueous extracts reduced the mitotic index, the seed germination and the root development of lettuce. The extracts have also induced chromosome aberrations and cellular death in the roots cells of L. sativa.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License