Anais da Academia Brasileira de Ciências | |
Identification of the antimicrobial substances produced by Solanum palinacanthum (Solanaceae) | |
Aline C. Pereira2  Denilson F. Oliveira2  Geraldo H. Silva1  Henrique C.p. Figueiredo1  Albero J. Cavalheiro1  Douglas A. Carvalho1  Luciana P. Souza2  Sára M. Chalfoun1  | |
[1] ,Universidade Federal de Lavras Departamento de Química Lavras MG ,Brasil | |
关键词: Solanum palinacanthum; 3; 5-dicaffeoylquinic acid; rutin; antimicrobial activity; Solanum palinacanthum; ácido 3; 5-dicafeoilquínico; rutina; antimicrobiano; | |
DOI : 10.1590/S0001-37652008000300004 | |
来源: SciELO | |
【 摘 要 】
To find out natural antimicrobial agents as alternative in therapeutics and to preserve food, the methanol extract of Solanum palinacanthum aerial parts was submitted to purification steps guided by antibacterial and antifungal assays. As a consequence, the flavonoid rutin and 3,5-dicaffeoylquinic acid were isolated by column chromatographyand high performance liquid chromatography, and identified by mass and nuclear magnetic resonance spectrometry. Minimal inhibitory concentrations (MIC) of the quinic acid derivative against Aeromonas hydrophila, Bacillus subtilis, Staphylococcus aureus and the fungus Aspergillus ochraceus were 250, 1000, 1000 and > 568µg/mL, respectively. Against the same microorganisms, MIC for rutin were 1000, > 1000, > 1000 and 35µg/mL, respectively. Rutinwas very promising for A. ochraceus control, since its MIC against such fungus was close to the one observed for benzalkonium chloride, which is used as a fungicide in Brazil.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202103040000636ZK.pdf | 173KB | download |