Frequency and enzymatic activity of Candida albicans isolated from the oral cavity of HIV-positive patients at Fortaleza, Ceará

Jornal Brasileiro de Patologia e Medicina Laboratorial

Everardo Albuquerque Menezes²  Maria Neuman Ricarte Monteiro¹  Ticiana Mont’alverne Parente¹  Francisco Afrânio Cunha¹  Kristopherson Lustosa Augusto¹  Caio César Furtado Freire¹ 

[1] ,Universidade Federal do Ceará Faculdade de Farmácia Odontologia e Enfermagem Departamento de Análises Clínicas e Toxicológicas

关键词: Candida albicans;    HIV;    Phospholipase;    Proteinase;    Candida albicans;    HIV;    Fosfolipase;    Proteinase;   

DOI  :  10.1590/S1676-24442006000400005

来源: SciELO

【 摘 要 】

Candida albicans and other species are usually involved in opportunistic infections in patients with acquired immunological deficiency syndrome (AIDS). The virulence mechanisms by which this yeast expresses its pathogenicity include adherence patterns, ability to form pseudomycelia and production of extracellular enzymes, among others. The objective of this research was to verify the frequency of Candida and the production of proteinase and phospholipase in 52 strains of Candida albicans from the oral cavity of patients infected by HIV treated at Hospital São José, AIDS reference and training center in Fortaleza, Ceará. Samples were collected of patients, with or without oral lesions characteristic of candidosis. From 100 patients, 80% presented positivity for Candida: 65% (52) were identified as C. albicans, 27.5% (22) as C. tropicalis, 2.5% (2) as C. glabrata, 2.5% (2) as C. krusei and 2.5% (2) as C. guilliermondii. Among the strains of C. albicans isolated from the oral cavity, proteinase and phospholipase were detected in 69.2% and 73%, respectively. The results suggested that C. albicans was the most frequent species observed, with intermediate expression of proteinase and phospholipase.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License