The effect of treatment with melatonin upon the ultrastructure of the mouse pineal gland: a quantitative study

Brazilian Journal of Biology

G. M. Redins¹  C. A. Redins¹  J. C. Novaes¹ 

[1],Universidade Federal do Espírito Santo Centro Biomédico Departamento de MorfologiaVitória ES ,Brazil

关键词: pineal gland;    melatonin;    ultrastructure;    glândula pineal;    melatonina;    ultra-estrutura;   

DOI  :  10.1590/S1519-69842001000400018

来源: SciELO

【 摘 要 】

In order to evaluate melatonin implication in the regulating of its own secretory process by pinealocytes, we used morphometric techniques for transmission electron microscopy. In mice treated with 100 mg of melatonin (N-acetyl-5-methoxy-tryptamine) by daily subcutaneous injection, we observed a decrease in number and volumetric density of lysosomes. Our results showed that melatonin influences the secretory activity of pinealocytes and participates in a complex secretory regulating mechanism.

【 授权许可】

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