Assessment of endothelial function by flow-mediated dilation of the brachial artery in adolescents with a history of preeclampsia or a normotensive pregnancy

Revista Brasileira de Saúde Materno Infantil

Joana Adalgisa Furtado Magalhães Andrade¹  Francisco Herlânio Costa Carvalho¹  Rosa Maria Salani Mota¹  Guilherme Augusto Magalhães Andrade¹  Helvécio Neves Feitosa¹  Flávio Lúcio Pontes Ibiapina¹  Francisco Das Chagas Medeiros¹ 

关键词: Pre-eclampsia;    Endothelium vascular;    Adolescent;    Ultrasonics;    Brachial artery;    Pré-eclâmpsia;    Endotélio vascular;    Adolescente;    Ultrassom;    Artéria braquial;   

DOI  :  10.1590/S1519-38292014000100008

来源: SciELO

【 摘 要 】

Objectives: to determine the prevalence of endothelial dysfunction and its association with a history of mild and severe preeclampsia in adolescents. Methods: a cross-sectional study was carried out at the MEAC-UFC with 103 primiparous adolescents postpartum. The assessment of endothelial function was performed by way of flow-mediated dilatation of the brachial artery. Variables (age, body mass index, gestational age at delivery, systolic and diastolic blood pressure and flow-mediated dilation) were compared between groups. p<0.05 was considered to be statistically significant. Results: twenty-four (23.3%) patients had preeclampsia (PE): 11 mild and 13 severe. The overall prevalence of endothelial dysfunction was 23.3% (21.5% of patients with normotensive pregnancies and 29.2% of the PE patients: 18.2% of those with mild PE and 38.5% of those with severe PE). The figures were statistically significant for systolic blood pressure, p=0.007. Conclusions: patients with a history of PE have higher systolic blood pressure than patients with a history of normotensive pregnancy, but did not have more endothelial dysfunction.

【 授权许可】

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