Cancer drugs inhibit morphogenesis in the human fungal pathogen, Candida albicans

Brazilian Journal of Microbiology

Madhushree M Routh¹  Nitin M Chauhan¹  S Mohan Karuppayil¹ 

[1] ,SRTM University School of Life Sciences ,India

关键词: Candida albicans;    morphogenetic switching;    cancer drugs;    antifungal antibiotics;   

DOI  :  10.1590/S1517-83822013000300029

来源: SciELO

【 摘 要 】

Candida infections are very common in cancer patients and it is a common practice to prescribe antifungal antibiotics along with anticancer drugs. Yeast to hyphal form switching is considered to be important in invasive candidiasis. Targeting morphogenetic switching may be useful against invasive candidiasis. In this study, we report the antimorphogenetic properties of thirty cancer drugs.

【 授权许可】

CC BY-NC   
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