Immunologic cross-reactivity between Muscovy duck parvovirus and goose parvovirus on the basis of epitope prediction

Brazilian Journal of Microbiology

Ming Li²  Tian-fei Yu¹ 

[1] ,Qiqihar University College of Computer and Control Engineering Qiqihar,P.R. China

关键词: MDPV;    GPV;    cross-reactivity;    prediction;    epitope;   

DOI  :  10.1590/S1517-83822013000200031

来源: SciELO

【 摘 要 】

Through bioinformatic prediction, between Muscovy duck parvovirus (MDPV) and goose parvovirus (GPV), there were one epitope AA503-509 (RANEPKE) on non-structural protein and three epitopes AA426-430 (SQDLD), 540-544 (DPYRS), 685-691 (KENSKRW) on structural protein might cross-react with each other. Furthermore, the four epitops were expressed in Escherichia coli. All the four recombinant proteins could react with GPV-antisera and MDPV-antisera in Western blot.

【 授权许可】

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