Stable expression and potential use of West Nile virus envelope glycoproteins preM/E as antigen in diagnostic tests

Brazilian Journal of Microbiology

Juliana Felipetto Cargnelutti²  Mário Celso Sperotto Brum¹  Rudi Weiblen²  Eduardo Furtado Flores² 

[1] ,Universidade Federal de Santa Maria Centro de Ciências Rurais Departamento de Medicina Veterinária PreventivaSanta Maria RS ,Brasil

关键词: West Nile virus;    WNV;    M/E glycoproteins;    stable expression;    diagnostic;   

DOI  :  10.1590/S1517-83822011000300040

来源: SciELO

【 摘 要 】

West Nile virus (WNV) envelope glycoproteins preM/E were stably expressed in baby hamster kidney cells and tested as antigen in a fluorescent antibody assay for WNV antibodies. Sera from horses, mice and chicken immunized with an inactivated WNV vaccine and, less consistently, sera from horses acutely infected with WNV, reacted specifically with viral antigens present in preM/E-expressing cells.

【 授权许可】

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