Evaluation of different methods for detecting methicillin resistance in Staphylococcus aureus isolates in a university hospital located in the Northeast of Brazil

Brazilian Journal of Microbiology

Francisco Canindé De Sousa Júnior²  Gildelane Da Silva Néri²  Ana Karine Silva²  Bibiana Priscila Rodrigues Câmara De Araújo²  Myrian Júlia De Paiva Dourado Guerra²  Maria José De Britto Costa Fernandes²  Eveline Pipolo Milan¹  Maria Celeste Nunes De Melo² 

[1],Universidade Federal do Rio Grande do Norte Centro de Biociências Departamento de Microbiologia e ParasitologiaNatal RN ,Brasil

关键词: MRSA;    methicillin resistance;    heterogeneous resistance;    cefoxitin;    PBP2a;   

DOI  :  10.1590/S1517-83822010000200009

来源: SciELO

【 摘 要 】

Many methods have been described for the detection of methicillin-resistant Staphylococcus aureus (MRSA), but the heterogeneous expression of methicillin resistance affects the reliability of these methods. The aim of the present study was to evaluate some methods for detecting methicillin resistance in Staphylococcus aureus isolates in a university hospital located in the Northeast of Brazil. Among the isolates, 15 were methicillin-susceptible and 45 were methicillin-resistant, including low-level heterogeneous resistance strains. Both the 30 µg-cefoxitin disk and PBP2a test had 100% sensibility/specificity and appear to be good options for the detection of MRSA in the clinical laboratory.

【 授权许可】

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