Microorganisms as tools in modern chemistry: the biotransformation of 3-indolylacetonitrile and tryptamine by fungi

Brazilian Journal of Microbiology

Maria Amélia D. Boaventura¹  Rosiane F.a.p. Lopes¹  Jacqueline A. Takahashi¹ 

[1] ,Universidade Federal de Minas Gerais Instituto de Ciências Exatas Departamento de QuímicaBelo Horizonte MG ,Brasil

关键词: Biotransformations;    Beauveria bassiana;    Aspergillus niger;    3-indolylacetonitrile;    tryptamine;    biotransformações;    Beauveria bassiana;    Aspergillus niger;    3-indolacetonitrila;    triptamina;   

DOI  :  10.1590/S1517-83822004000300014

来源: SciELO

【 摘 要 】

Chemical reactions performed by microorganisms have been used as a modern tool in chemistry. In this work, the ability of the fungi Beauveria bassiana and Aspergillus niger to modify the chemical structure of indole compounds was studied. Beauveria bassiana was able to transform 3-indolylacetonitrile into 3-methylindole while Aspergillus niger transformed tryptamine into 5-hydroxyindole-3-acetamide. Interestingly, these fungi were able to perform both reduction and oxidation of the indole compounds fed, the oxidation occurring with improved levels of oxygen uptake. The results prove once more the versatility of microorganisms to perform a wide range of industrially attractive chemical reactions.

【 授权许可】

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