SNPs genotyping technologies and their applications in farm animals breeding programs: review

Brazilian Archives of Biology and Technology

Hamed Kharrati Koopaee¹  Ali Esmailizadeh Koshkoiyeh² 

[1] ,Shiraz University Institute of Biotechnology ,Iran

关键词: SNPs genotyping;    Traditional and high throughput methods;    Animal breeding;   

DOI  :  10.1590/S1516-89132014000100013

来源: SciELO

【 摘 要 】

Single nucleotide polymorphisms (SNPs) are DNA sequence variations that occur when a single nucleotide: adenine (A), thymine (T), cytosine (C) or guanine (G) in the genome sequence is altered. Traditional and high throughput methods are two main strategies for SNPs genotyping. The SNPs genotyping technologies provide powerful resources for animal breeding programs.Genomic selection using SNPs is a new tool for choosing the best breeding animals. In addition, the high density maps using SNPs can provide useful genetic tools to study quantitative traits genetic variations. There are many sources of SNPs and exhaustive numbers of methods of SNP detection to be considered. For many traits in farm animals, the rate of genetic improvement can be nearly doubled when SNPs information is used compared to the current methods of genetic evaluation. The goal of this review is to characterize the SNPs genotyping methods and their applications in farm animals breeding.

【 授权许可】

CC BY-NC   
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