Mesenchymal stem cells: emphasis in adipose tissue

Brazilian Archives of Biology and Technology

Bruno Machado Bertassoli²  Antonio Chaves De Assis Neto¹  Franceliusa Delys De Oliveira¹  Maria Angélica Machado Arroyo¹  Juliana Shimara Pires Ferrão¹  Jodonai Barbosa Da Silva¹  Graciela Conceição Pignatari¹  Patrícia Beltrão Braga¹ 

[1] ,Universidade Federal de Minas Gerais Instituto de Ciências Biológicas PPG em Biologia CelularBelo Horizonte MG ,Brasil

关键词: Adipose Tissue;    Stem Cells;    Mesenchymal Stem Cells;   

DOI  :  10.1590/S1516-89132013000400011

来源: SciELO

【 摘 要 】

The study of stem cells has evolved rapidly in recent decades. The importance is given to the concept that these cells are potentially able to become any cell type and have the power of self-renewal throughout the life of the organism. Mesenchymal stem cells (MSCs) can be isolated from various organs of the body such as bone marrow, adipose tissue, synovium, muscle and dermis, deciduous teeth, umbilical cord, placenta, liver, spleen and thymus. After their isolation in vitro, mesenchymal stem cells have the capacity to differentiate into various mesenchymal lineages and various tissues after the use of appropriate cultures. Studies have reported that mesenchymal stem cells from adipose tissue have the potential to differentiate themselves, like the cells commonly studied bone marrow. Adipose tissue is attractive due to its easy access, rapid expansion in vitro and only one collects the large amount of tissue. This review intends to show the protocols for isolation, cell culture and means of commercial cellular differentiation most widely used with emphasis on adipose tissue.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License