In vitro inhibition of adhesion of Escherichia coli strains by Xylitol

Brazilian Archives of Biology and Technology

Annelisa Farah Da Silva²  Érika Yoko Suzuki²  Aline Siqueira Ferreira²  Murilo Gomes Oliveira²  Sílvio Silvério Da Silva¹  Nádia Rezende Barbosa Raposo² 

[1] ,Universidade Federal de Juiz de Fora Faculdade de Farmácia Juiz de Fora MG ,Brasil

关键词: Bacterial adhesion;    Escherichia coli;    Scanning electron microscopy;    Xylitol;   

DOI  :  10.1590/S1516-89132011000200003

来源: SciELO

【 摘 要 】

The present study aimed to evaluate xylitol's antimicrobial and anti-adherence activities on Escherichia coli (ATCC 8739) and on another clinical strain enteropathogenic E. coli (EPEC). In vitro minimum inhibitory concentration (MIC) test and adhesion assays were performed using 0.5, 2.5 and 5.0% xylitol. It was found that xylitol did not have antimicrobial properties on these strains. The scanning electron microscopy (SEM) demonstrated that the slides treated with xylitol had a significant reduction in the number of bacilli and the inhibition of microbial adhesion was probably the xylitol's mechanism of action. Xylitol could be a possible alternative on the control of E. coli infections.

【 授权许可】

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