Overview of parameters influencing biomass and bioreactor performance used for extracellular ligninase production from Phanerochaete chrysosporium

Brazilian Archives of Biology and Technology

Seteno Ntwampe²  Faysol Chowdhury¹  Marshall Sheldon¹  Heinrich Volschenk¹ 

[1] ,Cape Peninsula University of Technology Department of Agriculture and Food Sciences Cape Town,South Africa

关键词: Phanerochaete chrysosporium;    lignin peroxidase;    manganese peroxidase;    dissolved oxygen;    bioreactors;   

DOI  :  10.1590/S1516-89132010000500008

来源: SciELO

【 摘 要 】

The production of extracellular enzymes is gaining momentum as commercial interests seek alternative ways to improve the productivity in the biotechnology and pharmaceutical industries. Early research studies looked at improving batch bioreactor operational challenges; however, the use of continuous cultures was indicated to be favourable. This led to a new approach developed to produce extracellular enzymes continuously using fixed-film bioreactors from biofilms immobilised on polymeric and inorganic membranes. In this review, the performance of P. chrysosporium biomass, evaluated in terms of ligninase production using different bioreactor operation conditions, is highlighted. Furthermore, the limitations related to the implementation of optimised batch culture conditions to continuous fixed-film bioreactors are discussed. DO transportation, trace element toxicity and lipid peroxidation effects on P. chrysosporium biomass in fixed-film bioreactors operated for elongated periods, are also discussed.

【 授权许可】

CC BY-NC   
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