Sentinel lymph node detection through radioguided surgery in patients with breast cancer

Brazilian Archives of Biology and Technology

Benedita Andrade Leal De Abreu¹  Adriana De Morais Santos¹  Lívia De Almeida Soares¹  Antônio Ricardo Dos Santos¹  Idna De Carvalho Barros¹  Everardo Leal De Abreu¹  Alexandre Jorge Gomes Da Cruz Filho¹  João Batista De Abreu¹  Sabas Carlos Vieira¹ 

[1] ,Universidade Estadual do Piauí Centro Federal de Educação Tecnológica do Piauí

关键词: Breast cancer;    sentinel lymph node;    lymphoscintigraphy;    intraoperative probe;   

DOI  :  10.1590/S1516-89132008000700010

来源: SciELO

【 摘 要 】

Biopsy of the sentinel lymphnode (SLNB), the first lymphnode to receive lymphatic drainage from the primary tumor, accurately predicts the axillary lymph node status and, when negative, obviates the need for axillary lymphadenectomy (AL). The aim of this study was, to verify the SLN localization in breast cancer through preoperative lymphoscintigraphy and intraoperative gamma-probe, as well as to demonstrate the benefits of such techniques in preventing complications of AL. Medical records of 228 patients with breast carcinoma, who were underwent SLN localization and, radioguided surgery, from March 2005 to December 2007 were analyzed retrospectively. Data regarding age, tumor characteristic, breast involved, type of surgery, radiopharmaceutical drainage pattern, axillary assessment (SLNB or AL) and number of lymph nodes dissected were collected. It was ascertained that radioguided surgery is a selective method of axillary assessment in breast cancer, which makes this technique a safe alternative to radical assessment of total dissection of axillary lymph nodes and its subsequent complications.

【 授权许可】

CC BY-NC   
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