Extension of the IsaViz software for the representation of metabolic and regulatory networks

Brazilian Archives of Biology and Technology

Diogo Fernando Veiga²  Pedro De Stege Cecconello¹  José Eduardo De Lucca¹  Luismar Marques Porto² 

[1] ,Departamento de Engenharia Química e Engenharia de Alimentos Grupo de Engenharia Genômica

关键词: Metabolic and Regulatory Pathways;    RDF/XML;    Modeling;   

DOI  :  10.1590/S1516-89132005000400025

来源: SciELO

【 摘 要 】

In this work we developed an extension of IsaViz software, a RDF (Resource Description Framework) authoring tool, designed to be a graphical environment to build models of metabolic and regulatory networks. This environment, called Metabolic IsaViz, was linked to a genomic library of types and was modeled on the basis of ontologies. Biochemical pathways included data at sequence level (e.g., the amino acid sequence of enzymes), besides kinetic and thermodynamic parameters for the reactions. Models created with Metabolic IsaViz could be exported to pathways simulators through SBML (Systems Biology Markup Language), which allowed to analyze the pathway dynamics of target chemicals.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License