Isolated trisomy 11 in de novo acute myeloid leukemia

Revista Brasileira de Hematologia e Hemoterapia

Everson A. Krum¹  Tatiane Hamed¹  Mihoko Yamamoto¹  Maria De Lourdes Chauffaille¹ 

[1] ,Universidade Federal de São Paulo EPM São Paulo SP

关键词: Trisomy 11;    acute myeloid leukemia;    chromosomes;    Trissomia 11;    leucemia mielóide aguda;    cromossomos;   

DOI  :  10.1590/S1516-84842008000300016

来源: SciELO

【 摘 要 】

The real mechanism involved in trisomies and leukemogenesis remains unknown and more information about this connection is essential, but unfortunately the clinical outcome and hematological profile of patients with isolated trisomy 11 and AML have not been well characterized. Considering the limited data on the specific disease entity, the current report describes two cases of de novo acute monocytic leukemia (AMoL) and isolated +11, in which this event was further characterized.

【 授权许可】

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