Pure sarcomatous recurrence of clear cell renal carcinoma following radical nephrectomy and dendritic cell vaccination

Sao Paulo Medical Journal

Alberto Azoubel Antunes¹  Marcos Francisco Dall’oglio¹  José Alexandre Marzagão Barbuto¹  Kátia Ramos Moreira Leite¹  Miguel Srougi¹ 

[1] ,Universidade de São Paulo Faculdade de Medicina Division of Urology

关键词: Renal cell carcinoma;    Recurrence;    Sarcoma;    Nephrectomy;    Dendritic cells;    Carcinoma de células renais;    Recidiva;    Sarcoma;    Nefrectomia;    Células dendríticas;   

DOI  :  10.1590/S1516-31802006000300011

来源: SciELO

【 摘 要 】

CONTEXT: Sarcomatous differentiation, which represents transformation to high-grade malignancy, can occur in all histogical types of renal malignancy. CASE REPORT: The authors report on the case of a 66-year-old woman with a right renal mass that was shown to be a clear cell carcinoma. She underwent radical nephrectomy and dendritic cell vaccination and, 3.5 years later, she developed retroperitoneal pure sarcomatous recurrence of the tumor. The authors speculate that the vaccination could have played some role in this differentiation or selection of the sarcomatous component of the primary tumor.

【 授权许可】

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