Latent Autoimmune Diabetes of the Adult (LADA) in a Brazilian Indian

Sao Paulo Medical Journal

João Paulo Botelho Vieira Filho¹  Regina Célia Santiago Moisés¹  João Roberto De Sá¹  Antonio Roberto Chacra¹  Sergio Atala Dib¹ 

[1] ,Universidade Federal de São Paulo Escola Paulista de Medicina Department of Internal MedicineSão Paulo,Brazil

关键词: Diabetes Mellitus;    Autoantibodies;    Latent Autoimmune Diabetes of the Adult;    Brazilian;    Indian;    Diabetes Autoimune Latente do Adulto;    Índio;    Brasileiro;   

DOI  :  10.1590/S1516-31802001000200009

来源: SciELO

【 摘 要 】

CONTEXT: Latent autoimmune diabetes of the adult (LADA) as originally described represents perhaps as many as 10 -- 20% of adult-onset patients with diabetes. DESIGN: case report. CASE REPORT: A 38-year-old Brazilian Xavante-Jê Indian with Latent Autoimmune Diabetes of the Adult (LADA) is described, coming from the Sangradouro community in Poxoréu, Mato Grosso. The onset of diabetes after reaching 25 years of age, the evolution to insulin deficiency after a period of insulin-independence and the presence of auto-antibodies to glutamic acid decarboxylase (GAD) characteristic of LADA were present. This patient may represent the first case of LADA in a Brazilian with full Indian heritage. Further studies are necessary to verify the prevalence of this new type of diabetes in this population that does not have Caucasoid admixture and has a particular environmental background.

【 授权许可】

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