del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts

Sao Paulo Medical Journal

Maria De Lourdes Lopes Ferrari Chauffaille¹  José Tadeu Stéfano¹  Rosana Maria Valério¹  Maura Romeo¹  Maria Madalena Rodrigues¹  José Kerbauy¹ 

[1] ,UNIFESP Escola Paulista de Medicina São Paulo,Brazil

关键词: Myelodysplasia;    Iron overload;    Refractory anemia with ringed sideroblasts;    Karyotype;   

DOI  :  10.1590/S1516-31801997000400010

来源: SciELO

【 摘 要 】

We present the case of a patient with MDS RARS subtype with loss of part of the long arm of chromosome 11 del 11(q23). This a cytogenetic abnormality that occurs in 7% to 20% of RARS cases not related to poor prognosis. It seems that this deletion is a marker of iron overload in MDS.

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