HA/TCP scaffolds obtained by sucrose crystal leaching method: Preliminary in vitro Evaluation

Materials Research

Leonardo Ribeiro Rodrigues²  Marta De Sousa Laranjeira¹  Maria Helena Fernandes¹  Fernando Jorge Monteiro¹  Cecília Amélia De Carvalho Zavaglia² 

[1] ,Universidade Estadual de Campinas Faculdade de Engenharia Mecânica Departamento de Engenharia de MateriaisCampinas SP ,Brasil

关键词: hydroxyapatite;    calcium phosphate;    sucrose;    cell culture;    nanoparticles;   

DOI  :  10.1590/S1516-14392014005000082

来源: SciELO

【 摘 要 】

Scaffolds produced with ceramics are commonly used as bone substitute. In this work calcium phosphate materials were used to produce the scaffolds, because HA and TCP have many similarities with bone tissue. For crystalline phase analysis the scaffolds were calcined at 750 °C and sintered at 1330 °C. Electron microscopy images showed HA and TCP nanoparticles and the compounds were identified by Fourier transform infrared spectrometer. X-ray diffraction showed this material to be mostly crystalline. X-ray fluorescence identified chemical contaminants. X-ray micro computerized tomography produces tomographic images of the objects in 360°. In vitro testing was used to study cells behavior in contact with this material in a controlled environment.

【 授权许可】

CC BY   
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