In vitro study of cytotoxicity of orthodontic elastomeric ligatures

Materials Research

Rogério Lacerda Dos Santos²  Matheus Melo Pithon¹  Paulyana Pryscilla De Melo Freire²  Maria Teresa Villela Romanos¹ 

[1] ,Federal University of Campina Grande Department of Orthodontics Patos PB ,Brasil

关键词: cytotoxicity;    elastomers;    cell culture;    orthodontics;   

DOI  :  10.1590/S1516-14392012005000068

来源: SciELO

【 摘 要 】

This study investigated the cytotoxicity of crystal-coloured orthodontic elastomeric ligatures of polyurethane. Six ligatures from distinct manufactures were divided into 6 groups of 10 elastics each: Groups P1, P2, P3, P4, P5 and P6 (Polyurethane). The cytotoxicity essay was performed using L-929 line cells, which were submitted to the cell viability test with neutral red ("dye-uptake") at time intervals of 1, 2, 3, 7 and 28 days. Analysis of variance (ANOVA) with multiple comparisons and Tukey's test were used (p < .05). There were statistical differences (p < .05) in cell viability between Groups P1, P4, P2 and P3, and Groups P5 and P6 at 1 and 2 days. All elastomeric ligatures were considered suitable for clinical use. The hypothesis was accepted, the P5 and P6 elastomers and the processing route of injection molding for these ligatures showed the lowest cell viability, due the temperature and pressure distinct in the processing of these elastomers.

【 授权许可】

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