Porous titanium scaffolds produced by powder metallurgy for biomedical applications

Materials Research

Luana Marotta Reis De Vasconcellos²  Marize Varella De Oliveira¹  Mário Lima De Alencastro Graça¹  Luis Gustavo Oliveira De Vasconcellos²  Yasmin Rodarte Carvalho²  Carlos Alberto Alves Cairo¹ 

[1] ,State University of São Paulo São Jose dos Campos School of Dentistry Department of Bioscience and Buccal DiagnosisSão José dos Campos SP ,Brazil

关键词: biomedical;    porosity;    osseointegration;    titanium;   

DOI  :  10.1590/S1516-14392008000300008

来源: SciELO

【 摘 要 】

Porous titanium scaffolds are promising materials for biomedical applications such as prosthetic anchors, fillers and bone reconstruction. This study evaluated the bone/titanium interface of scaffolds with interconnected pores prepared by powder metallurgy, using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Porous scaffolds and dense samples were implanted in the tibia of rabbits, which were subsequently killed 1, 4, and 8 weeks after surgery. Initial bone neoformation was observed one week after implantation. Bone ingrowth in pores and the Ca/P ratio at the interface were remarkably enhanced at 4 and 8 weeks. The results showed that the interconnected pores of the titanium scaffolds promoted bone ingrowth, which increased over time. The powder metallurgy technique thus proved effective in producing porous scaffolds and dense titanium for biomedical applications, allowing for adequate control of pore size and porosity and promoting bone ingrowth.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License