Characterization of calcium phosphate coating and zinc incorporation on the porous alumina scaffolds

Materials Research

Hermes De Souza Costa¹  Marivalda Magalhães Pereira¹  Giovanna Ivo Andrade²  Edel Figueiredo Barbosa Stancioli²  Herman Sander Mansur¹ 

[1] ,Federal University of Minas Gerais Department of Metallurgical and Materials Engineering Laboratory of Biomaterials and Tissue EngineeringBelo Horizonte MG ,Brazil

关键词: scaffold;    bioceramics;    biomaterial;    alumina;    zinc;   

DOI  :  10.1590/S1516-14392007000100007

来源: SciELO

【 摘 要 】

Bone ingrowth requires materials with the existence of open and interconnected pores with diameters larger than 150 µm for proper circulation of nutrients. Such materials must possess enough mechanical strength to avoid failure whilst offering a bioactive surface for bone regeneration. We have developed porous ceramic alumina scaffold with compressive strength that achieves 3.3 MPa by replication method by using the network structure of cellular polymer foam. However, the biocompatibility of ceramics based on Al2O3 requires further improvement so that it could have strong bonding to natural bone tissue. To address this problem of the interface between alumina and bone, we have developed a novel calcium phosphate with Zn2+ (CaP-Zn) coating onto porous alumina ceramic scaffold by impregnating with calcium phosphate/poly(vinyl alcohol) slurry. The tri-dimensional alumina scaffold coated with CaP-Zn was extensively characterized by SEM, EDS and FTIR.

【 授权许可】

CC BY   
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