Quantitative trait loci (QTL) mapping for growth traits on bovine chromosome 14

Genetics and Molecular Biology

Marcelo Miyata²  Gustavo Gasparin²  Luiz Lehmann Coutinho¹  Mario Luiz Martinez¹  Marco Antonio Machado¹  Marcos Vinicius G. Barbosa Da Silva¹  Ana Lucia Campos¹  Tad S. Sonstegard¹  Millor Fernandes Do Rosário¹  Luciana Correia De Almeida Regitano¹ 

[1] ,Universidade Federal de São Carlos Programa de Pós-Graduação em Genética e Evolução São Carlos SP ,Brazil

关键词: TA14;    cattle;    F2;    growth traits;    molecular markers;    QTL;   

DOI  :  10.1590/S1415-47572007000300011

来源: SciELO

【 摘 要 】

Quantitative trait loci (QTL) mapping in livestock allows the identification of genes that determine the genetic variation affecting traits of economic interest. We analyzed the birth weight and weight at 60 days QTL segregating on bovine chromosome BTA14 in a F2 resource population using genotypes produced from seven microsatellite markers. Phenotypes were derived from 346 F2 progeny produced from crossing Bos indicus Gyr x Holstein Bos taurus F1 parents. Interval analysis to detect QTL for birth weight revealed the presence of a QTL (p < 0.05) at 1 centimorgan (cM) from the centromere with an additive effect of 1.210 ± 0.438 kg. Interval analysis for weight at 60 days revealed the presence of a QTL (p < 0.05) at 0 cM from the centromere with an additive effect of 2.122 ± 0.735 kg. The region to which the QTL were assigned is described in the literature as responsible for some growth traits, milk yield, milk composition, fat deposition and has also been related to reproductive traits such as daughter pregnancy rate and ovulation rate. The effects of the QTL described on other traits were not investigated.

【 授权许可】

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