期刊论文详细信息
Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society | |
Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury | |
关键词: viral; replication; NS1; PB1‐; F2; TRAIL; ARDS; | |
DOI : 10.1189/jlb.1011530 | |
学科分类:生理学 | |
来源: Federation of American Societies for Experimental Biology | |
【 摘 要 】
ProgrammedcelldeathisacrucialcellularresponsefrequentlyobservedinIV‐infectedtissue.Thisarticlereviewsthecurrentknowledgeonthemolecularvirus–hostinteractionsthatinduceapoptosispathwaysinanIV‐infectedcellandthefunctionalimplicationsofthesecellularsignalingeventsonviralpropagationatdistinctstepsduringtheviralreplicationcycle.Furthermore,itsummarizestheroleofIV‐inducedapoptosispathwaysinequilibratingthehostˈsantiviralimmuneresponsebetweeneffectiveviralclearanceanddevelopmentofsevereapoptoticlunginjury...
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
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RO201901237410855ZK.pdf | 811KB | download |