Genetic variability in geographical populations of Aedes aegypti (Diptera, Culicidae) in Brazil elucidated by molecular markers

Genetics and Molecular Biology

Karina Dos Santos Paduan²  João P. Araújo-júnior¹  Paulo E.m. Ribolla² 

[1] ,Universidade Estadual Paulista Instituto de Biociências Departamento de ParasitologiaBotucatu SP ,Brazil

关键词: Aedes aegypti;    population genetics;    random amplified polymorphic DNA;    genetic variability;   

DOI  :  10.1590/S1415-47572006000200030

来源: SciELO

【 摘 要 】

The tropical mosquito, Aedes aegypti is the most important domestic vector of urban yellow fever and dengue. Genetic population studies on this vector are important because they may lead to new tools for surveillance. An analysis of genetic structure was conducted among populations of A. aegypti from 11 localities in four demographic regions within six Brazilian federal states. Markers included 21 random amplified polymorphic DNA (RAPD) loci. RAPD markers were detected among populations and cluster analysis revealed two main groups. We found high genetic polymorphism (H S = 0.224) and high levels of genetic differentiation between populations from different states (G ST = 0.430), as well as in populations from cities in the same state (G ST = 0.410). These results indicate significant differentiation in A. aegypti populations in Brazil. Regression analyses of geographic distances and pairwise F ST values estimated from RAPD markers showed that there is a correlation between genetic structure and geographic localization.

【 授权许可】

CC BY   
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