Association of GH and IGF-1 polymorphisms with growth traits in a synthetic beef cattle breed

Genetics and Molecular Biology

Andréa Pozzi Pereira²  Maurício Mello De Alencar¹  Henrique Nunes De Oliveira¹  Luciana Correia De Almeida Regitano¹ 

[1] ,Universidade Federal de São Carlos Departamento de Genética e Evolução São Carlos SP ,Brazil

关键词: beef cattle;    genetic association;    genotype;    growth hormone;    insulin-like growth factor 1;   

DOI  :  10.1590/S1415-47572005000200009

来源: SciELO

【 摘 要 】

The Canchim beef cattle (5/8 Charolais + 3/8 Zebu) has been selected for meat production in Brazil since late 1950. In the present work the effects of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) polymorphisms were investigated in 688 animals born between 1998 and 2000. These animals belonged to two genetic groups, i.e., traditional and new lineages. Genotype effects on expected breeding values for birth weight (BW), weaning weight (WW) and yearling weight (YW) were investigated by the least square method. Significant effects were found for GH genotype on YW (p < 0.05), with positive effects associated with the LV (leucine/valine) genotype. For IGF-1 genotypes, significant effects were found on BW (p < 0.01) and YW (p < 0.01). Average substitution effects for IGF-1 alleles estimated by regression analysis suggested a positive effect of the IGF-1 225 bp allele on BW and of the 229 bp allele on YW.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License