Multidrug-resistant tuberculosis: case reports study in a central state of Brazil

Brazilian Journal of Infectious Diseases

João Alves De Araújo-filho²  Arioldo Carvalho Vasconcelos-jr²  Eduardo Martins De Sousa²  Colombina Da Silveira¹  Patrícia Tavares Pereira De Sousa¹  Klaus Andrade Severo¹  Ludmila Ferreira Vieira¹  André Kipnis²  Ana Paula Junqueira-kipnis² 

[1] ,Federal University of Goiás Institute of Tropical Pathology and Public Health

关键词: Tuberculosis;    multidrug-resistant tuberculosis;    MDR-TB;    Mycobacterium tuberculosis;   

DOI  :  10.1590/S1413-86702008000100020

来源: SciELO

【 摘 要 】

Multidrug-resistant tuberculosis (MDR-TB) is an emerging and worrisome health problem that threatens tuberculosis (TB) control worldwide. The clinical management of MDR-TB is a complex issue associated with the use of multiple drugs for a long period, usually accompanied by side effects and high costs. The objective of this work was to relate cases of MDR-TB occurring in Goiás, a central state of Brazil. We related five cases of MDR-TB, three women and two men. All were pulmonary cases. Three were in their second treatment and two in their first treatment. Surgical pulmonary resection was performed in one case. One death occurred. Lack of adherence, gastric intolerance to anti-TB drugs and poor clinical management were the main aspects related to the emergent resistance. A revision of the main clinical aspects of this disease was performed.

【 授权许可】

CC BY-NC-ND   
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