Brazilian Journal of Infectious Diseases | |
Antiretroviral therapy during pregnancy and early neonatal life: consequences for HIV-exposed, uninfected children | |
Patrícia El Beitune2  Geraldo Duarte2  Silvana Maria Quintana2  Ernesto A. Figueiró-filho2  Alessandra Cristina Marcolin2  Renata Abduch1  | |
[1] ,University of São Paulo Medical School of Ribeirão Preto Department of Obstetrics and Gynecology | |
关键词: HIV-1; exposed; infant; consequences; antiretroviral; | |
DOI : 10.1590/S1413-86702004000200004 | |
来源: SciELO | |
【 摘 要 】
Women have emerged as the fastest growing human immunodeficiency virus (HIV) infected population worldwide, mainly because of the increasing occurrence of heterosexual transmission. Most infected women are of reproductive age and one of the greatest concerns for both women and their physicians is that more than 1,600 infants become infected with HIV each day. Almost all infections are a result of mother-to-child transmission of HIV. With the advent of combination antiretroviral therapies, transmission rates lower than 2% have been achieved in clinical studies. Antiretroviral compounds differ from most other new pharmaceutical agents in that they have become widely prescribed in pregnancy in the absence of proof of safety. We reviewed antiretroviral agents used in pregnant women infected with human immunodeficiency virus, mother-to-child transmission, and their consequences for infants.
【 授权许可】
CC BY-NC-ND
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
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