Genética, biologia molecular e ética: as relações trabalho e saúde

Ciência & Saúde Coletiva

Gilka Jorge Figaro Gattás¹  Marco Segre¹  Victor Wünsch Filho¹ 

[1] ,Universidade de São Paulo. Faculdade de Medicina Departamento de Medicina Legal, Ética Médica e Medicina Social e do TrabalhoSão Paulo SP

关键词: Molecular genetics;    Workers health;    Ethics;    Genetic screening;    Genetic epidemiology;    Genética molecular;    Saúde do trabalhador;    Ética;    Rastreamento genético;    Epidemiologia genética;   

DOI  :  10.1590/S1413-81232002000100014

来源: SciELO

【 摘 要 】

This paper provides a discussion about the increasing development of genetics and molecular biomarkers technologies and consequent impact on practices of occupational health. Genetic analysis could be in specific populations at occupational, pharmacological or environmental exposures. Current knowledge of human genome open up the possibility of individual genetic screening of disease susceptibility among those exposed in workplaces to chemical or physical hazards, or for late onset hereditary disease. Epidemiological studies including genetic and molecular biology approaches have been designed to evaluate the interaction of genetically determined metabolic variants with different environmental exposures on the risk of diseases. The strategy for worker's health promotion must be maintained on the surveillance of hazardous exposure risks in occupational settings and not in worker's genetic screening. Ethical behavior in occupational health can vary from country to country and even between occupational health practitioners and researchers. To discuss the need for a social responsibility context in the use of genetic information in which ethical actions in occupational health could be conducted is the main purpose of this paper.

【 授权许可】

CC BY   
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