Anti-TNF-α and hydralazine drug-induced lupus

Anais Brasileiros de Dermatologia

Maria Victória Quaresma¹  Fred Bernardes Filho¹  Fernanda Brandão De Oliveira¹  Mercedes Prates Pockstaller¹  Maria Fernanda Reis Gavazzoni Dias¹  David Rubem Azulay¹ 

关键词: Acetyl-CoA C-Acetyltransferase;    Acetylation;    Autoimmunity;    Hydralazine;    Lupus erythematosus;    cutaneous;    Tumor necrosis factor-alpha;   

DOI  :  10.1590/abd1806-4841.20153893

来源: SciELO

【 摘 要 】

Abstract Drug-induced lupus is a rare drug reaction featuring the same symptoms as idiopathic lupus erythematosus. Recently, with the introduction of new medicines in clinical practice, an increase in the number of illness-triggering implicated drugs has been reported, with special emphasis on anti-TNF-α drugs. In the up-to-date list, almost one hundred medications have been associated with the occurrence of drug-induced lupus. The authors present two case reports of the illness induced respectively by hydralazine and infliximab, addressing the clinical and laboratorial characteristics, diagnosis, and treatment.

【 授权许可】

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