Chronic urticaria in adults: state-of-the-art in the new millennium

Anais Brasileiros de Dermatologia

Paulo Ricardo Criado¹  Roberta Facchini Jardim Criado¹  Celina Wakisaka Maruta¹  Vitor Manoel Silva Dos Reis¹ 

关键词: Angioedema;    Biological factors;    Colchicine;    Cyclosporine;    Dapsone;    Immunosuppressive agents;    Urticaria;   

DOI  :  10.1590/abd1806-4841.20153509

来源: SciELO

【 摘 要 】

Chronic urticaria has been explored in several investigative aspects in the newmillennium, either as to its pathogenesis, its stand as an autoimmune orauto-reactive disease, the correlation with HLA-linked genetic factors, especiallywith class II or its interrelation with the coagulation and fibrinolysis systems. Newsecond-generation antihistamines, which act as good symptomatic drugs, emerged andwere commercialized over the last decade. Old and new drugs that may interfere withthe pathophysiology of the disease, such as cyclosporine and omalizumab have beendeveloped and used as treatments. The purpose of this article is to describe thecurrent state of knowledge on aspects of chronic urticaria such as, pathophysiology,diagnosis and the current therapeutic approach proposed in the literature.

【 授权许可】

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