Clinical profile of patients with myasthenia gravis followed at the University Hospital, Federal University of Minas Gerais

Revista da Associação Médica Brasileira

Aline Mansueto Mourão¹  Luiz Sérgio Mageste Barbosa¹  Elizabeth Regina Comini-frota¹  Denise Da Silva Freitas¹  Rodrigo Santiago Gomez¹  Ted M. Burns¹  Stela Maris Aguiar Lemos¹  Antonio Lúcio Teixeira¹ 

关键词: myasthenia gravis;    epidemiology;    neurology;    thymectomy;    therapeutics;    miastenia gravis;    epidemiologia;    neurologia;    timectomia;    terapêutica;   

DOI  :  10.1590/1806-9282.61.02.156

来源: SciELO

【 摘 要 】

Summary Objective: to determine the clinical profile of patients with myasthenia gravis (MG); followed at the Neuromuscular Diseases Clinic of the University Hospital, Federal University of Minas Gerais, Brazil, and to compare it with other Brazilian case series. Methods: sociodemographic and clinical data were collected from patients, and a systematic literature review performed, focusing on national studies on the clinical profile of MG patients. Results: sixty nine patients were enrolled in the study. Fifty five (91%) subjects were female and the mean age (SD) was 37.6 (±11.4) years. The mean disease duration was 14.1 years. Regarding treatment, prednisone was the most used strategy (64%), followed by the use of azathioprine (43%). There was no difference between thymectomized (42) and non-thymectomized (27) patients regarding disease severity and medication use. Conclusion: clinical and socio-demographic features of this MG sample from a University-based clinic resemble those reported in other Brazilian series and in the international literature.

【 授权许可】

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