Guided bone regeneration with subperiosteal implants of PTFE and hydroxyapatite physical barriers in rats

Brazilian Dental Journal

Nelson Luiz De Macedo¹  Luís Guilherme Scavone De Macedo¹  Fábio Da Silva Matuda¹  Suzana Martins Ouchi¹  Adriana Socorro Ferreira Monteiro¹  Yasmin Rodarte Carvalho¹ 

[1] ,UNESP São José dos Campos School of Dentistry Department of Surgery, Periodontics and RadiologySão José dos Campos SP ,Brazil

关键词: guided bone regeneration;    wound healing;    polytetrafluoroethylene membrane;    hydroxyapatite;   

DOI  :  10.1590/S0103-64402003000200009

来源: SciELO

【 摘 要 】

Regeneration of periodontal and alveolar ridge defects utilizing membranes is a well-established procedure in reconstructive surgery. Biomaterial characteristics and membrane design employed in guided tissue regeneration (GTR) techniques play an important role in good results. The purpose of this histologic experimental study in rats was to compare the use of two physical barriers in the osteopromotion by using GTR principles in bone defects created in tibias. Fifteen animals divided into 3groups were used: group I (non-porous polytetrafluoroethylene (PTFE) barrier), group II (coral hydroxyapatite (HA) blocks), and group III (defects that received no physical barrier). Histological examination showed varied amounts of newly formed bone beneath both types of barriers. The non-porous PTFE barrier showed better results than the HA group. The results of this study suggest that bone regeneration can be successfully enhanced by a submerged membrane technique.

【 授权许可】

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