Activity of endodontic antibacterial agents against selected anaerobic bacteria

Brazilian Dental Journal

Cláudio Maniglia Ferreira¹  Odila Pereira Da Silva Rosa¹  Sérgio Aparecido Torres¹  Flaviana Bombarda De Andrade Ferreira¹  Norberti Bernardinelli¹ 

[1] ,University of Fortaleza Department of Endodontics Fortaleza CE ,Brazil

关键词: endodontics;    microbiology;    anaerobic bacteria;    antibacterial agents;    endodontia;    microbiologia;    bactérias anaeróbias;    agentes antimicrobianos;   

DOI  :  10.1590/S0103-64402002000200008

来源: SciELO

【 摘 要 】

The antimicrobial activity of substances used as antibacterial agents (solutions of 10% calcium hydroxide, camphorated paramonochlorophenol - PMCC, 2% chlorhexidine digluconate and 10% castor oil plant detergent) on anaerobic bacteria (Fusobacterium nucleatum ATCC 25586, Prevotella nigrescens ATCC 33563, Clostridium perfringens ATCC 13124 and Bacteroides fragilis ATCC 25285), using a broth dilution technique, was evaluated in vitro. For determination of minimum inhibitory and minimum bactericide concentrations (MIC and MBC), two culture broths, Reinforced Clostridial Medium (RCM) and supplemented Brucella, standardized inoculum and serially diluted solutions were used. All antibacterial agents presented antimicrobial activity that varied for different bacteria. There were no differences in the performance of the two broths. Chlorhexidine digluconate was the most effective, with the lowest MICs, followed by castor oil detergent, PMCC and calcium hydroxide. C. perfringens and B. fragilis were the most resistant bacteria to all agents.

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