Journal of the Brazilian Chemical Society | |
p-Cymenesulphonyl Chloride: A Bio-Based Activating Group and Protecting Group for Greener Organic Synthesis | |
Thomas J. Farmer1  James H. Clark1  Maite L. Gothe1  Duncan J. Macquarrie1  James Sherwood1  | |
关键词: citrus waste; p-cymene; sulphonyl chloride; activating group; protecting group; | |
DOI : 10.5935/0103-5053.20150169 | |
来源: SciELO | |
【 摘 要 】
A bio-derived protecting/activating group has been synthesized by introducing a sulphonyl chloride group to the aromatic ring of p-cymene derived from citrus peel waste. The resulting p-cymenesulphonyl chloride was evaluated as an activating group by reacting with 1-octanol, 2-octanol, phenol and piperidine, and further reactions of the activated alcohols. The comparison to tosyl chloride demonstrates that the bio-based alternative can be effectively utilized as a direct replacement for the current fossil derived equivalent.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
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RO202005130107749ZK.pdf | 333KB | download |