p-Cymenesulphonyl Chloride: A Bio-Based Activating Group and Protecting Group for Greener Organic Synthesis

Journal of the Brazilian Chemical Society

Sherwood, James¹  Gothe, Maite L.¹  Macquarrie, Duncan J.¹  University of York, Heslington, GB¹  Clark, James H.¹  Farmer, Thomas J.¹  Universidade de São Paulo, São Paulo, BR¹ 

关键词:  citrus waste;    p-cymene;    sulphonyl chloride;    activating group;    protecting group;   

DOI  :  10.5935/0103-5053.20150169

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

A bio-derived protecting/activating group has been synthesized by introducing a sulphonyl chloride group to the aromatic ring of p-cymene derived from citrus peel waste. The resulting p-cymenesulphonyl chloride was evaluated as an activating group by reacting with 1-octanol, 2-octanol, phenol and piperidine, and further reactions of the activated alcohols. The comparison to tosyl chloride demonstrates that the bio-based alternative can be effectively utilized as a direct replacement for the current fossil derived equivalent.

【 授权许可】

Unknown