Microwave-Assisted Synthesis of β-1,2,3-Triazolyl-α-amino Esters

Journal of the Brazilian Chemical Society

Amna N. Khan¹  Stanley N. S. Vasconcelos¹  Gonzalo Carrau¹  Hélio A. Stefani¹ 

关键词: microwave;    amino ester;    click chemistry;    addition reaction;    1;    2;    3-triazole;   

DOI  :  10.5935/0103-5053.20150114

来源: SciELO

【 摘 要 】

The reaction of ethyl (p-methoxyphenylimino)acetate with propargyl bromide mediated by activated zinc powder afforded alkynyl amine, which was then reacted with a variety of organic azides using a microwave energy source, leading to β-1,2,3-triazolyl-α-amino esters in good yield.

【 授权许可】

CC BY   
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