Ischemic stroke progress evaluation by 31P NMR-based metabonomic of human serum

Journal of the Brazilian Chemical Society

Caroline W. P. S. Grandizoli²  Marcos C. Lange¹  Felipe T. M. Novak¹  Francinete R. Campos¹  Andersson Barison² 

[1] ,Paraná Federal University Department of Chemistry NMR CenterCuritiba PR ,Brazil

关键词: 31P NMR;    metabonomic;    chemometric;    ischemic stroke;    diagnostic;    ischemic stroke biomarkers;   

DOI  :  10.5935/0103-5053.20140084

来源: SciELO

【 摘 要 】

In this work, chemometric analyses over 31P{¹H} NMR (nuclear magnetic ressonance) spectra of human blood serum permitted to discriminated ischemic stroke patients from health individuals due to changes in the chemical composition of phosphorus-containing compounds. These results indicate that 31P NMR-based metabonomic allowed insights over the mechanism triggered by ischemic stroke.

【 授权许可】

CC BY   
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