Phenolic compounds from the roots of Valeriana officinalis var. latifolia

Journal of the Brazilian Chemical Society

Peng-cheng Wang²  Xin-hui Ran²  Huai-rong Luo²  Qing-yun Ma¹  Yu-qing Liu²  Jun Zhou²  You-xing Zhao¹ 

[1] ,Chinese Academy of Sciences Kunming Institute of Botany State Key Laboratory of Phytochemistry and Plant Resources in West ChinaKunming,People's Republic of China

关键词: Valerianaceae;    Valeriana officinalis var. latifolia;    lignan;    chemical constituents;    acetylcholinesterase inhibitory;   

DOI  :  10.5935/0103-5053.20130184

来源: SciELO

【 摘 要 】

A new benzofuran neolignan, dihydrodehydrodiconiferyl alcohol 9-isovalerate, along with ten known phenolic compounds, olivil, pinoresinol, 8-hydroxypinoresinol, pinorespiol, 8-hydroxy7-epipinoresinol, trans-p-hydroxyphenyl- propenoic acid, cis-p-hydroxyphenyl-propenoic acid, ferulic acid, isoferulic acid and isovanillin were isolated from the roots of Valeriana officinalis var. latifolia. Their structures and configurations were elucidated on the basis of spectroscopic methods. The inhibitory activity for acetylcholinesterase (AChE) and enhancing activity on nerve growth factor (NGF)-mediated neurite outgrowth in PC12 cells of dihydrodehydrodiconiferyl alcohol 9-isovaterate and olivil were evaluated.

【 授权许可】

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