Phenolic compounds from the roots of Valeriana officinalis var. latifolia

Journal of the Brazilian Chemical Society

Liu, Yu-Qing¹  Ran, Xin-Hui¹  Luo, Huai-Rong¹  Zhou, Jun¹  Chinese Academy of Sciences, Kunming, People's Republic of China¹  Wang, Peng-Cheng¹  Ma, Qing-Yun¹  Zhao, You-Xing¹  Ministry of Agriculture, Haikou, People's Republic of China¹ 

关键词: Valerianaceae;    Valeriana officinalis var. latifolia;    lignan;    chemical constituents;    acetylcholinesterase inhibitory;   

DOI  :  10.5935/0103-5053.20130184

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

A new benzofuran neolignan, dihydrodehydrodiconiferyl alcohol 9-isovalerate, along with ten known phenolic compounds, olivil, pinoresinol, 8-hydroxypinoresinol, pinorespiol, 8-hydroxy7-epipinoresinol, trans-p-hydroxyphenyl- propenoic acid, cis-p-hydroxyphenyl-propenoic acid, ferulic acid, isoferulic acid and isovanillin were isolated from the roots of Valeriana officinalis var. latifolia. Their structures and configurations were elucidated on the basis of spectroscopic methods. The inhibitory activity for acetylcholinesterase (AChE) and enhancing activity on nerve growth factor (NGF)-mediated neurite outgrowth in PC12 cells of dihydrodehydrodiconiferyl alcohol 9-isovaterate and olivil were evaluated.

【 授权许可】

Unknown