Novel anthraquinone derivatives produced by Pestalotiopsis guepinii, an endophytic of the medicinal plant Virola michelii (Myristicaceae)

Journal of the Brazilian Chemical Society

Marilene N Oliveira²  Lourivaldo S Santos²  Giselle M. S. P Guilhon²  Alberdan S Santos²  Isabel C. S Ferreira²  Manoel L Lopes-junior²  Mara Silvia P Arruda²  Andrey M. R Marinho²  Milton N. Da Silva²  Edson Rodrigues-filho¹  Maria C. F Oliveira¹ 

[1] ,Universidade Federal do Pará Instituto de Ciências Exatas e Naturais Programa de Pós-Graduação em QuímicaBelém PA ,Brazil

关键词: Virola michelii;    Pestalotiopsis guepinii;    anthraquinone derivatives;    endophytic fungus;   

DOI  :  10.1590/S0103-50532011000500025

来源: SciELO

【 摘 要 】

A new anthraquinone derivative, named guepinone (1), along with the known substances isosulochrin (2) and chloroisosulochrin (3), were isolated from a rice culture of Pestalotiopsis guepinii, an endophytic fungus of Virola michelii. The compounds were identified by analysis of 1D and 2D NMR and MS spectral data. The antimicrobial activity of these compounds was evaluated and chloroisosulchrin (3) was the most active.

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