A simple synthesis of aminopyridines: use of amides as amine source

Journal of the Brazilian Chemical Society

Arumugam Kodimuthali²  Anitha Mungara²  Padala Lakshmi Prasunamba¹  Manojit Pal² 

[1] ,Anrich Industrial Estate New Drugs Discovery Department Matrix Laboratories Ltd,India

关键词: aminopyridine;    amide;    C-N bond;    chloropyridine;   

DOI  :  10.1590/S0103-50532010000800005

来源: SciELO

【 摘 要 】

A transition metal/microwave irradiation (or base) free synthesis of aminopyridines has been accomplished via C-N bond forming reaction between chloropyridine and a variety of simple amides under refluxing conditions.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License