Biological activities of lignoids from Amazon Myristicaceae species: Virola michelii, V. mollissima, V. pavonis and Iryanthera juruensis

Journal of the Brazilian Chemical Society

Sabrina K. R. Morais²  Ana F. Teixeira²  Zelina E. Dos S. Torres¹  Sergio M. Nunomura¹  Edite H. Yamashiro-kanashiro¹  José Angelo L. Lindoso¹  Massayoshi Yoshida² 

[1] ,Universidade de São Paulo Instituto de Química São Paulo SP ,Brazil

关键词: lignoids;    Iryanthera juruensis;    Virola michelii;    Virola mollissima;    Virola pavonis;    Myristicaceae;   

DOI  :  10.1590/S0103-50532009000600017

来源: SciELO

【 摘 要 】

This work revisits the fruits of Iryanthera juruensis and Virola pavonis and the leaves from V. michelii, as well as describing a study of the fruits of V. mollissima. In I. juruensis aryltetraline neolignan (1) and tetrahydrofuran neolignan (2), were found while from V. pavonis neolignans of benzofuran type (6-9), the tetrahydrofuran type (2, 11-13, 17) and the biphenyl type (10), in addition to diastereoisomers of the 8.O.4'-oxyneolignan type (14 and 15) and others were isolated. The V. mollissima accumulates the aryltetralone neolignan 4 and its seco derivative (5). The lignoids 1 and 2 obtained from I. juruensis arils possess antileishmanial activity against the promastigote form of Leishmania amazonensis.

【 授权许可】

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