Passerini multicomponent reaction of indane-1,2,3-trione: an efficient route for the one-pot synthesis of sterically congested 2,2-disubstituted indane-1,3-dione derivatives

Journal of the Brazilian Chemical Society

Ali Reza Kazemizadeh¹  Ali Ramazani¹ 

[1] ,Zanjan University Chemistry Department Zanjan,Iran

关键词: indane-1;    2;    3-trione;    isocyanide;    Passerini reaction;    benzoic acid;   

DOI  :  10.1590/S0103-50532009000200016

来源: SciELO

【 摘 要 】

The Passerini reaction of indane-1,2,3-trione, isocyanides and benzoic acid derivatives proceed at room temperature and sterically congested 2,2-disubstituted indane-1,3-dione derivatives are synthesized in excellent yields. The reaction proceeds smoothly and cleanly under mild conditions and no side reactions are observed.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License