Passerini multicomponent reaction of indane-1,2,3-trione: an efficient route for the one-pot synthesis of sterically congested 2,2-disubstituted indane-1,3-dione derivatives

Journal of the Brazilian Chemical Society

Kazemizadeh, Ali Reza¹  Zanjan University, Zanjan, Iran¹  Ramazani, Ali¹ 

关键词: indane-1;    2;    3-trione;    isocyanide;    Passerini reaction;    benzoic acid;   

DOI  :  10.1590/S0103-50532009000200016

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The Passerini reaction of indane-1,2,3-trione, isocyanides and benzoic acid derivatives proceed at room temperature and sterically congested 2,2-disubstituted indane-1,3-dione derivatives are synthesized in excellent yields. The reaction proceeds smoothly and cleanly under mild conditions and no side reactions are observed.

【 授权许可】

Unknown