Journal of the Brazilian Chemical Society | |
Chemical constituents of the underground stem bark of Duguetia furfuracea (Annonaceae) | |
Denise B. Da Silva1  Elaine C. O. Tulli1  Walmir S. Garcez2  Evandro A. Nascimento2  João M. De Siqueira1  | |
[1] ,Universidade Federal do Mato Grosso do Sul Departamento de Farmácia Campo Grande MS ,Brazil | |
关键词: alkaloids; Annonaceae; aporphines; duguetine beta-N-oxide; Duguetia furfuracea; sesquiterpenoids; | |
DOI : 10.1590/S0103-50532007000800017 | |
来源: SciELO | |
【 摘 要 】
In the present investigation the underground parts of Duguetia furfuracea (Annonaceae) were used to conduct a phytochemical study that included the brine shrimp (Artemia salina) lethality bioassay. The substances (-)-duguetine beta-N-oxide, (-)-duguetine, dicentrinone, (-)-N-methyltetrahydropalmatine, and (+)-N-methylglaucine were isolated from the alkaloid extract of the bark of the underground stem, and the ureide allantoin was also isolated by precipitation from the ethanol extract of the wood of the underground stem. A fresh volatile oil and a nonpolar extract were also obtained from the underground stem bark. The substances 2,4,5-trimethoxystyrene, a-gurjunene, aromadendrene, bicyclogermacrene, (E)-methylisoeugenol, and alpha-asarone were isolated from the fresh volatile oil and polycarpol, beta-caryophyllene oxide, 2,4,5-trimethoxystyrene, a-asarone, and asaraldehyde were obtained from the petroleum ether extract. The present study describes for the first time the alkaloid (-)-duguetine beta-N-oxide and the occurrence of (-)-N-methyltetrahydropalmatine and (+)-N-methylglaucine in the family Annonaceae. All extracts were active in the brine shrimp lethality bioassay.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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