Chemical composition and evaluation of antibacterial and antioxidant activities of the essential oil of Croton urucurana Baillon (Euphorbiaceae) stem bark

Journal of the Brazilian Chemical Society

Euclésio Simionatto²  Vanderléa F. L. Bonani²  Ademir Farias Morel¹  Nilva Ré Poppi¹  Jorge Luiz Raposo Júnior¹  Caroline Z. Stuker¹  Gisele M. Peruzzo²  Marize T. L. P. Peres²  Sônia C. Hess² 

[1] ,Universidade Federal de Mato Grosso do Sul Departamento de Hidráulica e Transportes Campo Grande MS ,Brazil

关键词: Croton urucurana;    essential oil;    antioxidant;    DPPH assay;    antimicrobial acticity;   

DOI  :  10.1590/S0103-50532007000500002

来源: SciELO

【 摘 要 】

The essential oil obtained from the stem bark of Croton urucurana Baillon (Euphorbiaceae) was analysed by GC and GC-MS. 83 compounds were identified and borneol (14.7%), bornyl acetate (5.2%), 1-isopropyl-7-methyl-4-methylene-1,3,4,5,6,8-hexahydro-2H-naphthalen-4a-ol (14.7%), sesquicineole (10.5%) and gamma-gurjunene epoxide (5.4%) were the main components. The EC50 value of the crude essential oil in the DPPH free radical scavenging assay was 3.21 mg mL-1. The fraction of the crude essential oil that presented antioxidant activity was purified by prep-TLC on silica gel. GC and GC-MS analysis revealed that alpha-bisabolol (38.3%), alpha-eudesmol (9.3%) and guaiol (8.2%) were the main components of the antioxidant fraction. The EC50 value measured for the bioactive oil fraction in the DPPH assay was 1.05 mg mL-1. The antimicrobial activity of the crude essential oil was assayed against seven Gram-positive and Gram-negative bacteria and three yeasts. Measured MIC values ranged from 1.25 to 10.00 mg mL-1.

【 授权许可】

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